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Aminocoumarin

Aminoglycoside

Antimetabolite

Beta-lactam

Bisindole

Cyclodipeptide

Isonitrile

Lincoside

NRPS-independent siderophore

Nucleoside

Phosphonate

Regulatory

RiPP

Nonribosomal peptide

Polyketide

Type II polyketide

Other

Cluster 9

NRPS-independent siderophore synthase
From search #20190318-1629-590782499
Sequence: DS999644.1.fasta

Biosynthetic assembly:

orf_2049 AMR116
orf_2055 NISc
orf_2061 AdpA

Cluster:

   

Legend:

Aminocoumarin

Aminoglycoside

Antimetabolite

Beta-lactam

Bisindole

Cyclodipeptide

CDPS active site

Deoxysugar

Isonitrile

Lincoside

Siderophore

Nucleoside

Phosphonate

Regulatory

Resistance

RiPP

Cleaved propeptide

Nonribosomal peptide

Polyketide

Hybrid

Type II polyketide

Tailoring

Bacteriocin

Other

Predicted cluster product:

Error: Unable to generate predicted structure!

Downloads:

Genomic cluster sequence: FASTA
Biosynthetic open reading frames: FASTA
All cluster open reading frames: FASTA
JSON report: JSON

Analysis

orf_2049

Domain Start End Score
Puromycin MFS transporter 1 478 218.3

Detection: predicted by Prodigal
Start: 2416089 | End: 2417589 | Frame: +

Sequence: show MSASPSPSRPSSDRMTGRAWGVLLVLCGAIFLEGIDVAMLNVALPAIREDLDLSTGTLQWVMSAYVLGYGGFMLLGGRAADLFGRRRMFVLWLVVFLLFSGLGGLATEGWVLIVARFVTGVAAAFMTPAGLSIITTGFPEGPRRDKALLVYAGTAAGGFSIGLVVGGLLSAIDWRWVFFAPVVLSLGILLAALALIPASPRPDRTGQGVDLAGAATVTAGILLLVFGVERATHVPAAWTVGTVGTALLLFLAFAAIERASSSPLVRPGIFRSGSLVRANAAGLLFAAGFFGFQFIVVLYLQELRGWSSLRTSFALIVIGVDAALSPLLTPKLVARFGHARVIFGGLLVASLSYALFLPLGADWTYAAMFPGLLLLGVAFSLVYGPLTIVATDGVAEAEQGVAGGLLHTSFQFGAALGLSAVTAVNIAATEGSSPAALLDGYRAALVIPLAAALIAAAVSAFGLRARRAEASASPAGGGGAPDRSDAPGGVEQPAGLGS (hide)

Domain analysis:

Biosynthetic assembly:

AMR116

orf_2055

Domain Start End Score
Type C NIS synthase 1 592 784.2

Detection: predicted by Prodigal
Start: 2422884 | End: 2424663 | Frame: +

Sequence: show MTTALTDSVAHLSPGRWATANRLLVRKALAEFSHERLLAPTPLGDDRFTVRSDDASTEYRFTARVFALDHWQVEAETITRHRHGSELPLDAVEFFIELRHTLGISEEILPVYLEEISSTLAGTAYKLTKEPATSGQLVAAGFQAVETGMTEGHPCFVANNGRLGFGVDEYRAYSPEAAAPIRLVWLAARRERATFTAGAGLDYDALVKDELSEATRERFAGALRGLGLEPDDYFLLPVHPWQWWNKLAVTFAGELAERHLVVLGQGEDGYLAQQSIRTFFNTDHPEKHYVKTALSVLNMGFMRGLSAAYMEATPAINDWLAGLIERDDLLRGARFSIIRERAAIGYHHRSYEAATAKGSPYRKMLAALWRESPVPGLQPGERVATMASLLHTDHEGTSVAGVLIAESGLDPQVWLRHYLDAYLVPVLHSFYAYDLVYMPHGENVILVVEDGVVTRTIFKDIAEEIAVMDPDAVLPPKVDRIRAEVPEDMKLLSVFTDVFDCFFRFLGAGLATEGVLDEATFWRTVAACVRDYQESVPYLAEKFAQYDLFEPEFALSCLNRLQLRDNQQMVDLNDPSGALQLVGRLKNPIAG (hide)

Domain analysis:

Biosynthetic assembly:

NISc

orf_2061

Domain Start End Score
Global activator of Strp production in S. griseus (activates StrR)) 1 405 914.3

Detection: predicted by Prodigal
Start: 2429458 | End: 2430676 | Frame: +

Sequence: show MSQDSATATEAARKLTGRRRREVVAVLLFSGGPIFESSIPLSVFGIDRQDAGVPRYRLLVCGGEEGPLRTTGGLELTTPYGLEAISRAGTVVVPAWRSITSPPPAEALDALRRAHEEGARIVGLCTGAFVLAAAGLLDGRPATTHWMYAPTLAKRYPSVHVDPRELFVDDGDVLTSAGTAAGIDLCLHIVRTDHGTEAAGALARRLVVPPRRSGGQERYLDRSLPEEIGSDPLAEVVAWALEHLHEQFDVETLAARAYMSRRTFDRRFRSLTGSAPLQWLITQRVLQAQRLLETSDYSVDEVAGRCGFRSPVALRGHFRRQLGSSPAAYRAAYRARRPQGVAESAATVVETTVPSQGPPPGRRGTPVSAAPVAVAASVGPGEHSLPGPDAFVPGRPALPGQRSA (hide)

Domain analysis:

Biosynthetic assembly:

AdpA