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Aminocoumarin

Aminoglycoside

Antimetabolite

Beta-lactam

Bisindole

Cyclodipeptide

Isonitrile

Lincoside

NRPS-independent siderophore

Nucleoside

Phosphonate

Regulatory

RiPP

Nonribosomal peptide

Polyketide

Type II polyketide

Other

Cluster 1

Nonribosomal peptide
From search #20190318-1629-590782499
Sequence: DS999644.1.fasta

Biosynthetic assembly:

orf_219 CGlyTCSerTEC

Cluster:

orf_219

Legend:

Aminocoumarin

Aminoglycoside

Antimetabolite

Beta-lactam

Bisindole

Cyclodipeptide

CDPS active site

Deoxysugar

Isonitrile

Lincoside

Siderophore

Nucleoside

Phosphonate

Regulatory

Resistance

RiPP

Cleaved propeptide

Nonribosomal peptide

Polyketide

Hybrid

Type II polyketide

Tailoring

Bacteriocin

Other

Predicted cluster product:

Combinatorial structure library: TXT or open in browser

GNP library: TXT

Combinatorial data evaluated:

  • Open reading frame permutations: 1
    (maximum 500)
  • Subgraph combinations: 1
  • Total combinatorial plans: 1 (maximum 1,000)
  • Scaffolds generated: 1 (maximum 50)

Downloads:

Genomic cluster sequence: FASTA
Biosynthetic open reading frames: FASTA
All cluster open reading frames: FASTA
JSON report: JSON

Analysis

orf_219

Domain Start End Score
Condensation+ 2 219 159.9
cdaps1_C6_LCL 268.0
cdaps2_C2_LCL 263.0
act3_C2_LCL 261.0
cdaps3_C2_LCL 260.0
cdaps1_C7_LCL 258.0
cdaps2_C3_LCL 258.0
act3_C3_LCL 256.0
prist2_C3_LCL 255.0
act2_C2_LCL 251.0
cyclom1C1_LCL 244.0
Adenylation+ 391 785 351.4
Glycine 23 394 808.6
Glycine 23 394 563.0
Threonine 23 394 489.3
Serine 23 394 483.3
Aspartate 23 394 479.6
Phenylalanine 23 394 478.7
Alanine 23 394 470.3
Arginine 23 394 465.4
Tryptophan 23 394 459.1
3-aminonon-5-enoic acid 4 394 111.1
Thiolation 893 957 48.0
Condensation+ 974 1280 234.9
prist2_C3_LCL 332.0
cdaps1_C7_LCL 325.0
cdaps1_C6_LCL 324.0
cdaps2_C2_LCL 320.0
cyclom1C2_LCL 316.0
act3_C2_LCL 315.0
cyclom1C4_LCL 313.0
act3_C3_LCL 313.0
cdaps2_C3_LCL 313.0
cyclom1C1_LCL 313.0
Adenylation+ 1446 1843 375.7
Serine 23 397 848.4
Alanine 23 397 633.1
Glutamate 23 397 574.4
Glycine 23 397 573.4
Aspartate 23 397 542.0
Threonine 23 397 533.8
Arginine 23 397 526.0
Lysine 23 397 521.8
Ornithine 23 397 517.9
α-ketoisovalerate 4 397 108.7
Thiolation 1952 2015 49.9
Epimerization+ 2054 2346 95.3
cdaps1_C4E 186.0
cdaps2_C4E 166.0
tioR_C2E 160.0
compl3_C4E 152.0
micro1_C2E 139.0
prist1_C3E 137.0
act2_C3E 126.0
compl3_C2E 125.0
surfa5_C4E 122.0
mycos2_C2E 119.0
Condensation+ 2531 2821 178.9
cdaps2_C1_DCL 275.0
compl3_C5_DCL 253.0
act3_C1_DCL 252.0
compl4_C1_DCL 250.0
cdaps1_C5_DCL 249.0
compl3_C1_DCL 245.0
cdaps3_C1_DCL 244.0
compl1_C1 233.0
compl2_C1_DCL 228.0
compl3_C3_DCL 224.0

Detection: predicted by Prodigal
Start: 280603 | End: 322129 | Frame: -

Sequence: show MDIGADALQERLDEAAGRPFDLAADLPVRATVFRLTDNDHILLLVLHHIAGDGWSMGPLARDLSTAYSARAAGAASAWRPLSVQYADYAAWQRDVLGTEDDESSELSAQLAYWRTQLASLPAELALPTDRARPAVATYRGGRIEFTIPADVHRSLADLARAEGVTVFMVVQAALAALLSRLGAGDDIPIGTPIAGRTDQATEDLIGFFVNTLVLRTDVSGDPTFAELLARVRATDLDAYAHQDIPFERLVEAVNPERSLARHPLFQVMLAFNNAETSTPLPMAEGLAASRQDIEPGVAKFDLALYCNESRGETGDHQGIRSVFEYRRDLWDEDTVRQLADRFLHVLAAFAAAPEQRASSVDVLRAGERDQLLHEWNDTAAALPPALLPQLFEEQVRRTPHDVALVSGNIRLTYAELDARANRLAHLLLARGAAPETFVAVALPRTEELLVALLAVQKTGAGHLPLDPGFPAERLSYMLDDARPAVVLTTEDISARIPGGSHVVLDSEQVTGELHDHPATSPAGRGNPAGPAYVIYTSGSTGQPKGVVVPSAALVNFLADMVPRLGLRGGDRLLSVTTVGFDIAALELFVPLLSGATVVLADGETVRDPALARQTCEDHGVTMVQATPSWWHGMLADAGDSLRGVHAVVGGEALSPGLRDALTRGARSVTNMYGPTETTIWSTSAGQAAGDSAPPSIGTPILNTRVYVLDAALCVVPPGVAGELYIAGDGLARGYLGRAGLTAERFVACPFGAPGERMYRTGDLVRWRVDGALEFVGRADDQVKVRGFRVELGEVEGAVAAHPDVVRAVVVVREDRPGDHRLVAYVTGVDTGGLSSAVMRAVAERLPAYMVPSAVVVLDEIPLTPNGKVDRAALPVPGVEAGAGYRAPVSPREEVLCGLFAEVLGVERVGVDDDFFGLGGHSLLATRLISRVRAVLGVEAGVRALFEAPTVSRLERLLRERSGLGVRVPLVARERTGREPLSFAQQRLWFLEELEGPGAAYNIPMALRLAGVLDVEALHQALIDVIARHESLRTLIARDSDGTARQQVLPVGDPAARPALPVVQTDADTLVAKLNEAVGRPFDLTAEMPLRATVFRVADEDHALLLVFHHIAGDGWSTGLLARDLSTAYAARLEGRDPQLPPLPVQYADYAAWQRDVLGTEDDESSELSAQLAYWRTQLADLPAELALPADRVRPARASYEGGRVGFTVPAGVLRDLTRLARVEGVTVFMVVQAALAALLSRLGAGDDIPIGTPIAGRTDQATEDLIGFFVNTLVLRTDVSGDPTFAELLARVRATDLDAYAHQDIPFERLVEAVNPERSLARHPLFQVMLAFDNTADGGPVEDFPGLSAAGLPLGAGAAKFDLLFGLSEVGGELRGAVEYRCDLFDHPTAARIAERLVRVLERVAADASVRLGELPVVSDAERACVLTEWNDTAVPGVTGTLSALFEARAAARGDAPAVVYEGEELSYRELNTRANRLAHVLAEHGAGPERFVGVALPRSPDLVVALLAVVKSGAAYVPLDPEYPADRLAYMAGDAAPVAVLTRGDVELPGSVPRIGLDDTEIRATLATAPGTNPGTPVTEAHPAYMIYTSGSTGRPKGVVVSHGAIVNRLAWMQAEYRLDATDRVLQKTPAGFDVSVWEFFWPLLEGAVLVFARPGGHRDAAYLAGLIERERITTAHFVPSMLRVFLEEPGAALCTGLRRVICSGEALGTDLAVDFRAKLPVPLHNLYGPTEAAVDVTHHAYEPATGTATVPIGRPIWNIRTYVLDAALRPVPPGVPGELYLAGAGLARGYHGRPALTAERFVACPFGVPGERMYRTGDLVRWRVDGTLEFVGRADDQVKVRGFRVELGEVEGAVAAHPDVVRAVVVVREDRPGDHRLVAYVTVGGVGGDGLRSAISGLVAERLPAYMVPSAVVVLDEIPLTPNGKVDRAGLPVPVVSVAGFCAPSSPREEVLCGLFAEVLGVERVGVDDGFFDLGGDSILSIQLVARARRAGLELSVRDVFEGRTVRALAAVVRGSDAGAVGVVGGAEIVLPGVGEVERWPVVEWLAERGGGSLGGVVRGFNQSVVLAVPAGLVWEELRVLLGAVRDRHEAWRLRVLDSGALCVDGVVPDDGSWIVRCDLSGMGVDGQVDAVRAAAVEARAWLDPSVGRVVRAVWLERGGDRSGVLVLVAHHLVVDGVSWRVVLGDLAEGWAQVRSGGRVELGVVGTSLRGWAAALAEQGRRGERAGEVELWSRMVRGADVLVGSRAVDGAVDVFGGVVSVDSRASVSVSRALLTEVPSVLGVGVQEVLLAAFGLAVARWRGRGGPVVVDVEGHGRNEDAVRGADLSRTVGWFTSVYPVRVPVESASWDEVRAGGPVVGRVVREVKETLRSLPDQGLGYGILRYLDPEHGPALARHATPQFGFNYLGRFTTGTDDTGDALDRAPAWSLLARSAAGQDPELPVAHAVEFNAITLDTPEGPRLGVTWSWPTTLLPESRIRELARYWDEALEGLVEHARHPEAGGLTPSDVTLVEVNQVELDRLQAGVAGGAEEILPVSALQEGLLFHSALASGGVDVYVGQLVFDLVGPVDVDRLRAAVEGLVARHGVLRSGYRQLRSGEWVAVVARQVDLPWQSIDVRDGGIDGLVEEERWRRFDMGRGPLARFVLIRTHDDRFRFVITYHHVVLDGWSVPVLLRELLALYGSSGDVSVLPGVRSYGDFLRWVAARDAAAAEGAWRRALTGLEEPSLVAPGVSRDGVVPAAFHGAVDGDLSQKIVAWARGRGVTVASVVQAAWALVLGRLMGRDDVVFGVTVSGRPAEVVGVEDMVGLFVNTIPLRARLPAESLGGFVERLQREQTELLEHQHVRLAEVQRWAGHKELFDVGMVFDNYPVSSESPEAEFQISRTGGYNGTHYALNLVASMHGLELELEIGYRPDVFDAGRVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX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(hide)

Domain analysis:

Biosynthetic assembly:

CGlyTCSerTEC